The upside and down side of mental illness and pharmaceuticals based on profiles and companies that endorse pharmaceuticals

For the use and treatment of severely disabled and handicapped profiles . 

Facts based on the stigmata subject information gathered relative and non relative non case studies and no trials, test subjects. 

Comparative cross examinations of how pharmaceuticals work on region of the brain.

A thirty one year personal recollection and notation of progresses and failures of the mental health succession.

Written by ; ms t Jo Gwin - dykema

2013/ November 

Let's start with astra Zeneca and doctor Conrad Murray , the Michael Jackson case.

Propofol vs 

Seroquel tablets and Seroquel XL prolonged-release tablets both contain the active ingredient quetiapine, which is a type of medicine known as an atypical antipsychotic. Quetiapine is also available without a brand name, ie as the generic medicine.

Quetiapine works in the brain, where it affects various neurotransmitters, in particular serotonin (5HT) and dopamine. Neurotransmitters are chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells.

Dopamine and serotonin are neurotransmitters known to be involved in regulating mood and behaviour, amongst other things. Psychotic illness is considered to be caused by disturbances in the activity of neurotransmitters (mainly dopamine) in the brain. Schizophrenia is known to be associated with an overactivity of dopamine in the brain, and this may be associated with the delusions and hallucinations that are a feature of this disease.

Quetiapine works by blocking the receptors in the brain that dopamine acts on. This prevents the excessive activity of dopamine and helps to control schizophrenia.

Schizophrenic patients may experience 'positive symptoms' (such as hallucinations, disturbances of thought, hostility) and/or 'negative symptoms' (such as lack of emotion and social isolation). Quetiapine is effective in relieving both positive and negative symptoms of schizophrenia, whereas the conventional antipsychotics are usually less effective against the negative symptoms.

Quetiapine is also used by specialists to treat episodes of mania and depression in people with the psychiatric illness, bipolar affective disorder (manic depression).


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